Computational Biologist
Company: 3DC
Location: New York
Posted on: June 25, 2022
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Job Description:
Computational Biologist
US-NY-New York
Job ID: 2021-1668
Type: Regular Full-Time
# of Openings: 1
Category: Research & Development
3DC
Overview
Deerfield Discovery and Development, LLC (3DC) engages in drug
discovery research in collaboration with premier universities and
biopharmaceutical companies across the United States. 3DC is the
drug discovery arm of Deerfield Management Company, L.P.
("Deerfield"), an investment firm dedicated to advancing
healthcare. The goal of 3DC is to enable portfolio companies of
Deerfield's investment funds to create a pipeline of medically
important and commercially viable projects at a scale sufficient to
produce value for patients and investors. Project teams consist of
scientists from a wide variety of disciplines (chemistry, biology,
DMPK, toxicology, computational science, software and automation
engineering), working together in a highly collaborative
environment to advance these goals.
Responsibilities
We are seeking a Computational Biologist to work with Matt Nelson,
Vice President of Genetics and Genomics, to help develop novel
insights into the role that genes play in disease and apply them to
novel target discovery, target validation, portfolio
prioritization, and to support private and public investment
activities. This position is open to all levels of experience for
candidates with a minimum of three years conducting bioinformatics
research in the context of drug discovery and development.
Take a leading role in the integration of insights from genetic and
genomic data to support the identification of new drug targets, the
review of proposed targets, the ongoing validation of existing
targets, and identification of potential patient selection
biomarkers The ideal candidate will have recent experience
supporting oncology drug discovery
Provide hands-on support to build out DF genetics and genomics
databases
Develop analytics for common genetic and genomic data use cases and
help integrate them into reusable applications
Provide genomic data analysis as needed to support DF discovery
project review and progression, including consulting with academic
labs to ensure sound methods and interpretation of data
Provide bioinformatics consulting for Deerfield portfolio companies
that lack internal expertise
Provide training to Deerfield staff, portfolio companies, and
collaborators in genomics applications
Participate in the development of the Deerfield drug discovery and
development data strategy, including genetics, genomics, assays,
chemistry, and clinical data
Contribute to private investment due diligence
Contribute to evaluation of clinical development programs
Qualifications
Minimum qualifications
PhD or equivalent training in computational biology,
bioinformatics, biostatistics, genetics, or related area
Five years post-graduate research experience, including three years
working in target discovery, target validation, and related
applications to drug discovery, including work in oncology
Extensive experience conducting hands-on genomic data analysis with
tools such as R, Python, and command-line tools
Broad knowledge of public and private genomic data sources and
state-of-the-art analysis methods and tools
Preferred qualifications
Experience working in or leading multidisciplinary teams
Publication record in peer reviewed journals
Strong understanding of genetic concepts and genome-wide approaches
to genetic data analysis and interpretation
3DC provides equal employment opportunities (EEO) to all employees
and applicants for employment without regard to religion, race,
creed, color, sex, sexual orientation, alienage or citizenship
status,
PM18
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Keywords: 3DC, New York , Computational Biologist, Other , New York, New York
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